Statistical significance is a critical concept in data analysis and research. In essence, it’s a measure that allows researchers to assess whether the results of an experiment or study are due to ...

Significance testing, with appropriate multiple testing correction, is currently the most convenient method for summarizing the evidence for association between a disease and a genetic variant.

Figure 1: Independent substitutions on a tree can create confounding covariations. Figure 2: Covariation analysis of known or proposed RNA secondary structures. Failure to identify significant ...