In a two-color experiment (panel a in the figure) DNA from individuals of the same species or different tissue from a single individual (e.g., normal and diseased cells) is extracted and ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. The microarray is a very recent development in the field of biotechnology. Scientists are now able to understand the gene functions of any organism by ...

Consider the ranking of genes using data from replicated microarray time course experiments, where there are multiple biological conditions, and the genes of interest are those whose temporal profiles ...

With the prevalence of gene expression studies and the relatively low reproducibility caused by insufficient sample sizes, it is natural to consider joint analysis that could combine data from ...

Microarrays provide a method of quantifying the expression and order of genes in a particular genome -- acting as a surrogate measure of cell physiology, said researchers at Baylor College of Medicine ...

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

The first study of the use of microarray patches to vaccinate children has shown that the method is safe and induces strong immune responses. The phase 1/2 randomized trial compared results from the ...

Expression noise is inherent to microarray-based measurement of gene expression. Noise can be defined as gene expression variation that does not correlate with the biology or behavior being studied ...

Reviewed by Dr. Tomislav Meštrović, MD, Ph.D. Microarray or biochip is a lab-oriented microscope slide that is usually made of glass, silicon chip, or nylon membrane. It is a 2D array (sometimes 3D) ...

A US research collaboration has successfully adapted an ArrayIt Spotbot, usually used to monitor protein activity, to print bacteria. In doing so, the researchers have delivered an experimental ...

JA Rosenfeld is an employee of Signature Genomic Laboratories, a subsidiary of PerkinElmer, Inc. The authors have no other relevant affiliations or financial involvement with any organization or ...