Microarrays have been described as a technology that will revolutionise medicine with the ultimate goal to develop effective treatments or cures for every human disease by 2050 (Ioannidis, 2005a). It ...

Microarray expression profiling is instrumental to our understanding of the function of the genome. Resolution of functionally relevant expression patterns will require the analysis of large data sets ...

In microarray gene expression experiments, several diverse conditions in each experiment (e.g., time, doses, replicates) increase the data points from tens of thousands of measurements for a single ...

Chemotherapy and Survival Benefit in Elderly Patients With Advanced Non–Small-Cell Lung Cancer Identifying sources of variation in expression microarray data and the effect of variance in gene ...

Expression Analysis says it has completed a significant milestone in a “mock-submission of microarray data” being prepared for the FDA. The company also has named Thomas Goralski as laboratory ...

With the prevalence of gene expression studies and the relatively low reproducibility caused by insufficient sample sizes, it is natural to consider joint analysis that could combine data from ...

Consider the ranking of genes using data from replicated microarray time course experiments, where there are multiple biological conditions, and the genes of interest are those whose temporal profiles ...

The research community's rapid acceptance of microarrays notwithstanding, technical challenges remain. Biochip developers continue to grapple with these issues while upgrading their offerings and ...

Although the superiority of expression-based biomarkers, as compared with traditional clinical staging, has been disputed, 33 a nationwide clinical trial is under way in the Netherlands in which ...

Ron Peterson, lab head at Novartis Institutes of Biomedical Research, is preparing for a wave of new studies using microarrays. A workhorse genetic testing tool called a microarray got a lot more ...

The power and promise of microarrays are vast. Offering the ability to run tens of thousands of experiments in parallel on a small glass slide, gene chips have transformed functional genomics, whether ...