The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...

For the first time, researchers have succeeded in developing an artificial DNA base pair that is based on a different ...

A research team at the University of Cologne has developed an artificial DNA base pair that works according to a new chemical principle. In contrast to natural bases, the novel artificial base pairs ...

A refined base-pair editor limits unintended neighboring DNA edits while maintaining strong correction of disease-causing mutations. The technology could advance treatments for cystic fibrosis and ...

Base pairs are at the heart of molecular biology information. Recognized ever since their discovery by Watson and Crick in 1953, the base pair provides, among other things, rules for copying DNA, ...

A team led by Professor Shoichiro Asayama at Tokyo Metropolitan University has synthesized a charge-free molecule designed to sneak plasmid DNA into living cells via hydrogen bonding, dramatically ...

Base pairing is a very specific process which can be used to design matching strands. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by ...

Study Shows How Melting Point Analysis Infers the Presence of and Identifies SNPs The melting temperature (T m) of a PCR product is dependent on both the length and sequence of the DNA. Melting curve ...

Beam Therapeutics focuses on base editing technology, which allows for precise changes at the DNA level and potentially reduces off-target effects. Base editing has the versatility to correct a wide ...